Megaloblastic Anaemia

Also Known As:

What is Megaloblastic Anaemia?

Megaloblastic Anaemia is a blood disorder which occurs when bone marrow produces abnormally structured red blood cells that are too large and too young. This leads to a lack of healthy red blood cells needed to carry adequate oxygen throughout the body.


Megaloblastic Anaemia is caused by a lack of Vitamin B12 and/or Folate. Your body needs these vitamins to produce healthy red blood cells.


The most common symptom of Megaloblastic Anaemia is fatigue. Symptoms can vary from person to person, and these include:
•   Shortness of breath
•   Muscle weakness
•   Abnormal paleness of the skin
•   Glossitis
•   Loss of appetite leading to weight loss
•  Diarrhoea
•   Nausea
•   Fast heartbeat
•   Tingling and numbness in hands and feet

Diagnosis & Treatment

Megaloblastic Anaemia is diagnosed by a Doctor using a physical examination, blood tests, and in some cases a Schilling Test may be conducted.

Your treatment plan can also depend on your age and overall health as well as your response to treatments and how severe the disease is. Treatment to manage Megaloblastic Anaemia is often ongoing and can include:
•   Vitamin B12 injections
•   Supplements and changes in diet

Additional Information

Also see: Anaemia, Vitamin Deficiency Anaemia

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Published Date:

10th December 2018


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